Here's a tweak I did in Vista 64-bit to help with my latency, originally at speedguide.net > articles > registry tweaks. As far as I know, it works in XP and Vista as long as you have SP2 (XP) or SP1 (Vista) respectively. (Check the bottom of the article)

It wasn't an incredible improvement but I've noticed my ping is anywhere from 20-35ms lower most of the time, particularly in Dragon Rising, CoD4 and L4D.

Anyway, here's the tweak below. Follow it step by step and be sure to reboot once you're done, then boot the game back up and see if you notice an improvement.




Gaming Tweak - Disable Nagle's algorithm

The tweak below allows for tweaking or disabling Nagle's alogrithm. Disabling "nagling" allows for very small packets to be transferred immediately without delay. Note that disabling Nagle's algorithm is only recommended for some games, and it may have negative impact on file transfers/throughput. The dafault state (Nagling enabled) improves performance by allowing several small packets to be combined together into a single, larger packet for more efficient transmission. While this improves overall performance and reduces TCP/IP overhead, it may briefly delay transmission of smaller packets. Keep in mind that disabling Nagle's algorithm may have some negative effect on file transfers, and can only help reduce delay in some games. To implement this tweak, in the registry editor (Start>Run>regedit) find:

This setting configures the maximum number of outstanding ACKs in Windows XP/2003/Vista/2008:
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Servic es\Tcpip\Parameters\Interfaces\{NIC-id}
There will be multiple NIC interfaces listed there, for example: {1660430C-B14A-4AC2-8F83-B653E83E8297}. Find the correct one with your IP address listed. Under this {NIC-id} key, create a new DWORD value:
TcpAckFrequency=1 (DWORD value, 1=disable, 2=default, 2-n=send ACKs if outstanding ACKs before timed interval. Setting not present by default).

For gaming performance, recommended is 1 (disable). For pure throughput and data streaming, you can experiment with values over 2. If you try larger values, just make sure TcpAckFrequency*MTU is less than RWIN, since the sender may stop sending data if RWIN fills witout acknowledgement.

Also, find the following key (if present):
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\MSMQ\Paramet ers
Add a new DWORD value:
TCPNoDelay=1 (DWORD value, 0 to enable Nagle's algorithm, 1 to disable, not present by default)

To configure the ACK interval timeout (only has effect if nagling is enabled), find the following key:
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Servic es\Tcpip\Parameters\Interfaces\{NIC-id}
TcpDelAckTicks=0 (DWORD value, default=2, 0=disable nagling, 1-6=100-600 ms). Note you can also set this to 1 to reduce the nagle effect from the default of 200ms without disabling it.

Notes:
Reportedly, the above gaming tweak (disabling nagle's algorithm) can reduce WoW (World of Warcraft) latency by almost half!
XP/2003 needs hotfix or SP2 for it to work (MS KB 815230)
Vista needs hotfix or SP1 for it to work (MS KB 935458)