You know, the point of setting up your own UI is that you know where everything is when you need it.

Personally I'm fine with the stock WoW UI with a few tweaks. The addons I get don't really take up much space, can be run in the background, or pulled up on request.

CTRa is 'on request' because the vanilla health bars you get from dragging them off the raid tab are smaller and easier to spot check.
KTM is 'on request' because I've played a hunter to long I don't really need it to manage my aggro. Aside from that, we hardly have someone dedicated to managing it so it doesn't matter.
Decursive works in the background. You can ditch the interface and use the hotkey.
Damage meters (SW or whatnot) works in the background and can be pulled on cue. Basically its a good idea not to see it so you don't fixate on it.

Otherwise I just map things to how I like it using the 4 bars and the 0-9 keys Blizzard gave us. Here's a tip: Shift+# will switch between the 6 bars so hitting Shift-1 and Shift-2 can quickly shift between two different load outs and Shift-3 through Shift-6 can shuffle through the other 4 bars. Then you just hit the 0-9 key you map what you want and you're golden.


Some quick tips for your UI would be as follows:
1) Make the background and boarder vanish behind Res Monitor so you can stash it somewhere without the blue background getting in the way.
2) You don't need KTM in Razorgore.
3) Why do you have your character picture taking up the bottom of your screen? O.o
4) Swap your Titan bar from the bottom of the screen to the top. Having all that information cramed with your buttons makes it look crowded. Placing it on the top also gives your eyes more exercise since it will cause you to look from the top to the bottom and make what you put in the middle more meaningful to you.